![]() In addition, they contain antimicrobial proteins, since platelets have the ability to interact with microbes, being an important part of the defense against infections. Each plate has 50 to 80 of these granules. Specifically, we find three types of granules inside this blood element: alphas, dense, and lysosomal.Īlpha granules are responsible for housing a series of proteins that are involved in hemostatic functions, including platelet adhesion, blood clotting, and endothelial cell repair, among others. In the central region of the platelet we find several organelles, such as mitochondria, endoplasmic reticulum and Golgi apparatus. These help with clotting and preventing potential damage to blood vessels. In each microliter of circulating blood, we find more than 300,000 platelets. Platelets can exhibit certain heterogeneity in their characteristics, without this being the product of any disorder or medical pathology. Under normal conditions, platelets respond to cellular and humoral stimuli, acquiring an irregular structure and a sticky consistency that allows adherence between their neighbors, forming aggregates. However, when blood preparations treated with some substance that inhibits clotting are observed, the platelets take a more rounded shape. Platelets in circulation usually exhibit a biconvex morphology. Its metabolism is very active and its half-life is a little over a week. They are considered to be small - their dimensions are between 2 to 4 um, with an average diameter of 2.5 um, measured in an isotonic buffer.Īlthough they lack a nucleus, they are complex elements at the level of their structure. Platelets are disc-shaped cytoplasmic fragments. Not only do they participate in aspects related to blood coagulation, but they also release antimicrobial proteins, which is why they are involved in defense against pathogens.Ĭharacteristics and morphology Platelets overview Platelets form a kind of "bridge" between hemostasis and the processes of inflammation and immunity. Each megakaryocyte will progressively fragment and give rise to thousands of platelets. ![]() The cells that give rise to platelets are called megakaryocytes, a process orchestrated by thrombopoietin and other molecules. They are involved in hemostasis - the set of processes and mechanisms that are responsible for controlling bleeding, promoting coagulation. The platelets or thrombocytes They are cell fragments of irregular morphology that lack a nucleus and we find them forming part of the blood. Incomplete cell division of megakaryocytes.Video: Platelets (Thrombocytes) | The Cell Pieces That Lack Nucleus Content
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